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EP 991B - Pancreatic Cancer: New "Time Machine" Science

Summary: A pancreatic cancer “time machine” engineered by Purdue University researchers has revealed that the disease is even more unpredictable than previously thought.
Air Date: 5/12/20
Duration: 19:36
Host: Michael Roizen, MD
Guest Bio: Bumsoo Han, PhD
Bumsoo Han is a Professor of Mechanical Engineering and Biomedical Engineering at Purdue University.  He is also B.S.F. Schaefer Outstanding Young Faculty Scholar and Discovery Park Fellow at Birck Nanotechnology Center.  He serves as Leader of Drug Delivery and Molecular Sensing Program of NCI-designated Purdue Center for Cancer Research.  He received his Ph.D. in Mechanical Engineering from the University of Minnesota, and his M.S. and B.S. from Seoul National University in Korea.  After his Ph.D., he was a Post-doctoral Research Associate in Mechanical and Biomedical Engineering at the University of Minnesota.  His research interests are in biotransport phenomena for cancer therapy and tissue engineering.  He received US DOD Postdoctoral Award for Breast Cancer Research, NSF CAREER Award, Faculty Fellowship from US Air Force Research Laboratory (Predictive Toxicology Program), and Richard Skalak Best Paper Award from ASME Journal of Biomechanical Engineering.  Recently, he is the recipient of Faculty of Excellence Early Career Research Award from Purdue University, and Brain Pool Korea Fellowship from Ministry of Science of South Korea.
    EP 991B - Pancreatic Cancer: New "Time Machine" Science
    Pancreatic cancer has one of the worst survival rates among cancers. Patients can expect as low as a nine percent chance to live for at least five years after being diagnosed.

    Going back in time to observe how cells with key gene mutations interact and become invasive would help researchers better understand how the cancer starts and identify it sooner.

    A pancreatic cancer “time machine” engineered by Purdue University researchers has revealed that the disease is even more unpredictable than previously thought: Cancer cells promote each other’s invasiveness when they grow together.

    Bumsoo Han, PhD, joins Dr. Roizen to explain more about this science. 

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